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xiao qing long tang gai shan leng xiao xing zhi qi guan xiao chuan qi dao zhong su de lin chuang yan jiu
Author(s): 
Pages: 20-22
Year: Issue:  6
Journal: ACTA CHINESE MEDICINE AND PHARMACOLOGY

Keyword:  支气管哮喘气道重塑小青龙汤;
Abstract: 目的:观察小青龙汤对改善支气管哮喘患者气道重塑的临床疗效.方法:将具有典型临床表现的支气管哮喘患者62例随机分为2组,治疗组服用小青龙汤;对照组予以爱全乐雾化吸入治疗.结果:显示2组总有效率比较无显著性差异(P>0.05),2组治疗都能改善患者的症状、体征和肺功能,治疗前后对比有显著性差异(P<0.05);小青龙汤在降低患者血清嗜酸性粒细胞(EOS)水平和肺功能方面要优于对照组,有显著性差异(P<0.05).结论:小青龙汤可明显改善支气管哮喘患者的临床症状,能有效降低患者EOS水平,减轻气道高反应状态.提示小青龙汤可能通过抑制炎性介质的释放,改善粘膜水肿和管腔阻塞程度,抑制基层细胞增生和平滑肌增厚,阻断气道重塑.
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