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Effect of Jiannao Yishou Capsule on SOD and GSH - Px in serum of senile mice
Author(s): 
Pages: 38-39
Year: Issue:  6
Journal: ACTA CHINESE MEDICINE AND PHARMACOLOGY

Keyword:  健脑益寿胶囊D-半乳糖SODGSH-Px;
Abstract: 目的:探讨健脑益寿胶囊的抗衰老作用机制.方法:以D-半乳糖所致亚急性衰老模型小鼠为模型,随机分6组,分别灌胃给予健脑益寿胶囊高剂量组2.08g/kg,中剂量组1.04g/kg,低剂量组0.52g/kg;阳性对照药维生素E 0.0078g/kg;空白对照生理盐水10ml/kg.6周后,测定血清中超氧化物歧化酶(SOD)及谷胱甘肽过氧化物酶(GSH-Px)的活性.结果:与模型组比较,健脑益寿胶囊可明显提高衰老模型小鼠血清中SOD及GSH-Px的活性.结论:健脑益寿胶囊具有明显的抗衰老作用,其作用机理可能与提高抗氧化酶的活性,对抗自由基的生成有关.
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