The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit
later.
We apologize for any inconvenience caused
Relationship between Human Age and mtDNA 4977 Deletions in Human Blood Cells
Author(s): LI Cheng-tao, LI Li, LIU Yan
Pages: 346-
348
Year: 2006
Issue:
5
Journal: JOURNAL OF FORENSIC MEDICINE
Keyword: 线粒体 DNA; mt DNA 4977缺失; 年龄; 相关性;
Abstract: 目的 检测不同年龄组人活体血细胞线粒体DNA 4977碱基缺失情况及其与年龄的相关性.方法 根据Anderson标准序列设计mtDNA恒定区和mtDNA4977特异缺失区引物,采用实时荧光定量PCR技术,对110份不同年龄组人活体血细胞mtDNA4977缺失水平进行检测.结果 在23岁以下个体中未检出mtDNA4977缺失,在大于23岁的被检个体中检测到mtDNA4977缺失,年龄越大,越容易检测到缺失.结论 人mtDNA4977缺失与年龄有一定的相关性.
Citations
No citation found
Related Articles
No related articles found