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jian fei diao zhi jiao nang zhi liao dan chun xing fei pang bing ( wei re shi zu xing ) de lin chuang yan jiu
Author(s): 
Pages: 69
Year: Issue:  4
Journal: JOURNAL OF HENAN UNIVERSITY OF CHINESE MEDICINE

Abstract: 目的:探讨减肥调脂胶囊对单纯性肥胖病的作用机理,为中医药治疗该病提供可靠的临床依据.方法:选择符合单纯性肥胖病西医诊断标准和胃热湿阻型肥胖病中医诊断标准的肥胖病人75例,随机分为三组,即A组(饮食运动组)25例,B组(饮食运动+月见草油胶丸组)25例,C组(饮食运动+减肥调脂胶囊组)25例.在治疗前和治疗60日后观察体重、BMI、皮褶厚度、F%、腰围、臀围、腰臀比、FBG、TC、TG、LDL-C、HDL-C、Leptin、INS等指标和临床症状变化情况.结果:从体重、BMI、皮褶厚度、F%、腰围、臀围看,三组治疗前后比较,差异均有显著性(P<0.05或P<0.01),但各组前后下降差值比较,C组优于A组、B组(P<0.01),A组与B组差异无显著性(P<0.05).实验室观察指标表明:治疗后三组的FBG、TC、TG、LDL-C、HDL-C、Leptin、INS均降低,HDL-C升高,各组前后比较均有显著性差异(P<0.05或P<0.01).结论:减肥调脂胶囊能明显降低患者体重及BMI,减少皮褶厚度、腰臀围、降低F%,可显著降低患者的FBG、TC、LDL-C,升高HDL-C,该药可显著降低患者的Leptin、INS水平,改善胰岛素抵抗、瘦素抵抗,能明显改善临床症状.
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