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Study on release of compound Ganshu patches
Author(s): 
Pages: 60-63
Year: Issue:  4
Journal: WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE AND MATERIA MEDICA

Keyword:  复方肝舒贴释放渗透;
Abstract: 本文旨在研究复方肝舒药物的体外释放速度和药物中化学成分自身经皮渗透特性.复方肝舒用医用胶制备成为贴剂,体外释放速度和经皮渗透特性分别通过药典释放度方法和Franz扩散池法进行考察.体外释放研究结果表明,复方肝舒贴制剂中黄芪甲苷在2h释放率约为5%,12h释放超过70%,此后释放速度逐渐放缓;莪术醇24h累计释放超过50%;没药和王不留行中成分也有不同程度释放.经皮渗透结果表明,莪术、郁金和没药中所含成分能够穿过裸鼠皮肤.
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