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Dissection of Cavernous Nerves in Rat and Model of Neurological Erectile Dysfunction
Author(s): WANG Fei-Xiang, ZHANG Ling-Li, ZHU Guang-You
Pages: 183-
185,封底
Year: 2006
Issue:
3
Journal: JOURNAL OF FORENSIC MEDICINE
Keyword: 海绵体神经; 勃起功能障碍; 大鼠;
Abstract: 目的对大鼠海绵体神经进行解剖并制作损伤致神经性ED的动物模型.方法通过10只废弃大鼠的解剖了解海绵体神经的解剖结构,将30只雄性SD大鼠分为实验组和对照组,术后一个月通过低频电刺激证实造模是否成功.结果大鼠海绵体神经解剖结构与人体非常相似,位于盆神经节的下方,电刺激海绵体神经,勃起试验阳性,造模后勃起试验阴性(P<0.01).结论由于大鼠海绵体神经分布与人体有高度相似性,且价格适合,是ED研究的理想动物,海绵体神经损伤是建立神经性ED的可靠方法.
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