Bovine jugular venous conduit treated with the polyepoxy compound
Author(s): XU Zhao-jun, WU Zhong-shi, HU Tie-hui, HU Jian-guo, FENG Yao-guang, MA Zhong-sha, WANG Hui, HU Jian, HU Ye-rong
Pages: 355-358
Year: 2006 Issue: 3
Journal: JOURNAL OF CENTRAL SOUTH UNIVERSITY (MEDICAL SCIENCES)
Keyword: 牛; 颈静脉; 环氧化合物; 交联;
Abstract: 目的:探讨采用环氧化合物交联新型肺动脉血管替代物之一牛颈静脉带瓣管道(BJVC)的方法和效果.方法:新鲜BJVC 24根,随机分为环氧化合物处理组(PC组,n=8),戊二醛处理组(GA组,n=8)及新鲜对照组(n=8).分别测量各组处理前后管壁厚度、管腔外径及瓣膜的抗返流功能的变化.测定处理前后各组的组织含水量、热皱缩温度、组织断裂强度及断裂伸长率.另外进行大鼠皮下埋植试验,60d后测定组织钙含量.结果:PC组外观形态、管腔外径、瓣膜抗返流功能更接近天然血管;PC组及GA组机械性能相当,且明显强于新鲜对照组(P<0.05);大鼠皮下包埋后PC组钙含量显著低于GA组P<0.05).结论:PC交联BJVC可有效保持组织的柔软性,保护其瓣膜的抗返流性能,且具备良好的抗钙化性能,是一种有效的合适的生物组织处理制备的新型技术.
Pages: 355-358
Year: 2006 Issue: 3
Journal: JOURNAL OF CENTRAL SOUTH UNIVERSITY (MEDICAL SCIENCES)
Keyword: 牛; 颈静脉; 环氧化合物; 交联;
Abstract: 目的:探讨采用环氧化合物交联新型肺动脉血管替代物之一牛颈静脉带瓣管道(BJVC)的方法和效果.方法:新鲜BJVC 24根,随机分为环氧化合物处理组(PC组,n=8),戊二醛处理组(GA组,n=8)及新鲜对照组(n=8).分别测量各组处理前后管壁厚度、管腔外径及瓣膜的抗返流功能的变化.测定处理前后各组的组织含水量、热皱缩温度、组织断裂强度及断裂伸长率.另外进行大鼠皮下埋植试验,60d后测定组织钙含量.结果:PC组外观形态、管腔外径、瓣膜抗返流功能更接近天然血管;PC组及GA组机械性能相当,且明显强于新鲜对照组(P<0.05);大鼠皮下包埋后PC组钙含量显著低于GA组P<0.05).结论:PC交联BJVC可有效保持组织的柔软性,保护其瓣膜的抗返流性能,且具备良好的抗钙化性能,是一种有效的合适的生物组织处理制备的新型技术.
Citations
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