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Heat shock protein gp96 and tumor immunological therapy
Author(s): 
Pages: 1-4
Year: Issue:  1
Journal: JOURNAL OF INTERNATIONAL ONCOLOGY

Keyword:  热休克蛋白质类肿瘤免疫疗法抗原提呈;
Abstract: 热休克蛋白(HSP)gp96是一种高度保守的蛋白质,具有分子伴侣功能,参与MHC-Ⅰ类抗原的提呈.肿瘤来源的gp96-肽复合物免疫活性强,可诱发抗相应肿瘤细胞的MHC-Ⅰ类限制性CD8+细胞毒性T细胞免疫应答,为肿瘤免疫治疗开辟了一条新的途径.
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