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Inhibitors of angiogenesis in the treatment of colorectal cancer
Author(s): 
Pages: 54-57
Year: Issue:  1
Journal: JOURNAL OF INTERNATIONAL ONCOLOGY

Keyword:  血管生成诱导新生血管化病理性大肠肿瘤;
Abstract: 血管生成是大肠癌生长、转移过程中必不可少的环节,抗血管生成治疗是大肠癌治疗中一个很有希望的靶点.血管内皮生长因子(VEGF)是最重要的肿瘤血管形成因子之一,已研究出多种治疗策略来抑制VEGF途径,早期研究显示针对VEGF的单抗Bevacizumab具有抗血管生成作用,特别是与化疗联合应用治疗晚期大肠癌疗效显著.
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