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Progression of activator protein-1 and colorectal cancer
Author(s): 
Pages: 58-60
Year: Issue:  1
Journal: JOURNAL OF INTERNATIONAL ONCOLOGY

Keyword:  结肠肿瘤直肠肿瘤激活蛋白1信号传导;
Abstract: 结直肠癌的发生是一个复杂的、多步骤的过程.激活蛋白1的活化和肿瘤的增殖、侵袭与转移有关.近年来的研究已经认识到激活蛋白1与结直肠癌密切相关.激活蛋白1通路调节环氧合酶-2合成,并参与脱氧胆酸诱导的结直肠癌的发生过程.因此,干预激活蛋白1的活性已成为结直肠癌治疗的新靶点.
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